Welcome to POSTAR2

POSTAR2 is a comprehensive database for exploring post-transcriptional regulation based on CLIP-seq data, Ribo-seq data, RNA-seq data and other high-throughput sequencing data from 6 species, including human, mouse, fly, worm, Arabidopsis, and yeast. POSTAR2 is developed as the updated version of CLIPdb and POSTAR, which provides the largest collection of RBP binding sites and functional annotations.

POSTAR2 provides three modules: (i)“RBP” module, which provides annotations and functions of RBPs, as well as RBP binding sites; (ii) “RNA” module, consisting of several sub-modules including “Binding sites”, “Crosstalk”, “Variation” and “Disease”, which annotates the RBP binding sites using various regulatory events and genomic variants; (iii) “Translatome” module, which aims for exploring the translation landscape of genes across different tissues and cell lines.

Email: postar2 AT googlegroups.com

News

POSTAR2 released in June, 2018.

Expanded to 6 species, including human, mouse, fly, worm, Arabidopsis and yeast.

Built a new module “Translatome”, which contains 35 million ORFs among 6 species and involves 177 Ribo-seq datasets and 123 RNA-seq datasets.

Added ~23 million RBP binding sites identified from ~500 CLIP-seq datasets.

Updated RNA modification, RNA editing and some other post-transcriptional regulatory data.

Updated genomic variants and disease-associated variants data.

Provided a more user-friendly “help” module which contains detailed tutorials to ensure an easier use.

POSTAR 1.0 released in April, 2016.

POSTAR beta released in July, 2015.

CLIPdb released in September, 2014.

Citation

POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins. Hu B*, Yang YT*, Huang YM, Zhu YM and Lu ZJ NAR (2017)

CLIPdb: a CLIP-seq database for protein-RNA interactions. Yang YT*, Di C*, Hu B*, Zhou M, Song N, Li Y, Liu Y, Umetsu J and Lu ZJ BMC Genomics. (2015)16:51.