About Translatome Module

The Translatome module characterizes the translation landscape using Ribo-seq data. POSTAR3 returns a summary frame, with histogram showing number of different types of ORF, and a heatmap showing density in different conditions. Tables contain ORF of different types, and each ORF could be linked to their density, translation efficiency(TE), identified translation region, and ribosome profiling signal.

2. RiboCode: Xiao Z, Huang R, Xing X, Chen Y, Deng H, Yang X. De novo annotation and characterization of the translatome with ribosome profiling data. Nucleic Acids Res. 2018;46(10):e61.
3. RiboTaper: Calviello L, Mukherjee N, Wyler E, et al. Detecting actively translated open reading frames in ribosome profiling data. Nat Methods. 2016;13(2):165-170.
4. ORFscore: Bazzini AA, Johnstone TG, Christiano R, et al. Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation. EMBO J. 2014;33(9):981-993.