Immune Diseases

I. Reviews

✅ [review] 2024 Nature Immunology - The immunology of systemic lupus erythematosus
[review] 2023 Nature Reviews Nephrology - Genetics of SLE: mechanistic insights from monogenic disease and disease-associated variants
[review] 2023 Nature Reviews Rheumatology - Precision medicine in systemic lupus erythematosus
[review] 2023 Nature Reviews Rheumatology - Post-transcriptional checkpoints in autoimmunity
[review] 2022 Nature Reviews Rheumatology - The role of mitochondria in rheumatic diseases

2024 Cell Reports Medicine - Uncoupling interferons and the interferon signature explains clinical and transcriptional subsets in SLE
2022 Signal transduction and targeted therapy - Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopenia
✅ 2022 Science - Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus
✅ 2022 Cell - Distinct transcriptome architectures underlying lupus establishment and exacerbation
✅ 2021 Cell - Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases
2022 Nature Med - Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
2021 PNAS - The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients
2020 Nature Immunology - Mapping systemic lupus erythematosus heterogeneity at the single-cell level
2019 Nature - Analysis of the B cell receptor repertoire in six immune-mediated diseases

✅ 2023 Immunity - Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection
✅ 2023 Nature - Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
2023 Nature cell biology - Single-cell analysis reveals transcriptomic and epigenomic impacts on the maternal– fetal interface following SARS-CoV-2 infection
2022 Cell Reports - Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus
2021 Science Immunology - Integrated single-cell transcriptomics and epigenomics reveals strong germinal center–associated etiology of autoimmune risk loci

2022 Nature Leukemia - Single-cell ATAC-seq maps the comprehensive and dynamic chromatin accessibility landscape of CAR-T cell dysfunction

(SLE biomarker) 2022 Lancet Rheumatol - Identification of biomarkers to stratify response to B-cell-targeted therapies in systemic lupus erythematosus: an exploratory analysis of a randomised controlled trial