Interaction-seq
I. RNA-RNA
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2025 Nature communications biology - Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing
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✅ [review] 2024 Molecular Cell - Technological advancements in deciphering RNA-RNA interactions
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✅ 2024 Cell - snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification
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✅ 2024 Nature Biotechnology - KARR-seq reveals cellular higher-order RNA structures and RNA–RNA interactions
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2023 Nature - Complementary Alu sequences mediate enhancer–promoter selectivity
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[review] 2022 Current Opinion in Genetics & Development - Architecture of RNA–RNA interactions
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✅ 2020 Nature - RIC-seq for global in situ profiling of RNA–RNA spatial interactions
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✅ 2020 Nature - RIC-seq for global in situ profiling of RNA–RNA spatial interactions.
II. RNA-DNA+
- ✅ MUSIC-seq: 2024 Nature - Single-cell multiplex chromatin and RNA interactions in ageing human brain
- 2024 Nature Leukemia - The landscape of RNA-chromatin interaction reveals samll non-coding RNAs as essential mediators of leukemia maintenance
- 2022 Nature Protocols - SPRITE: a genome-wide method for mapping higher-order 3D interactions in the nucleus using combinatorial split-and-pool barcoding
- 2017 Nature Biotech. - GRID-seq reveals the global RNA–chromatin interactome
III. Off-target
1. Screen methods
- 2024 Nature Biotechnology - Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling
2. sgRNA offtarget - experimental methods
- 2024 Nat. Biotech. - Tracking-seq reveals the heterogeneity of off-target effects in CRISPR–Cas9-mediated genome editing
- 2023 Nat. Methods - Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq+
- 2019 Science - Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq